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This information should not be used to decide whether or not to take amlodipine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about amlodipine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to amlodipine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using amlodipine.

About amlodipine

The kidneys are a pair of organs located in the back of the abdomen. Each kidney is about 4 or 5 inches long -- about the size of a fist. When Should I Call My Doctor? Your doctor or may already be aware of any possibledrug interactions and may be monitoring you for them. not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Vincent J, Harris SI, Foulds G et al. Lack of effect on grapefruit juice on the pharmacokinetics and pharmacodynamics of amlodipine. Br J Clin Pharmacol.

Report prolonged or to your doctor

Pfizer Laboratories. Norvasc amlodipine besylate tablets prescribing information. New York; 2015 Mar. Can use the fixed combination as a substitute for the individually administered drugs. 129 Can switch to the fixed-combination preparation containing the corresponding individual doses of amlodipine and telmisartan; alternatively, can increase the dosage of one or both components for additional antihypertensive effects. Horton R. Spinning the risks and benefits of calcium antagonists. Lancet. If BP is controlled with amlodipine and benazepril administered separately can switch to the fixed-combination preparation containing the corresponding individual doses for convenience.

Amlodipine adult dosage

Check your blood pressure and pulse heart rate regularly while taking this medication. Learn how to check your own blood pressure and pulse at home, and share the results with your doctor. It is not known whether carvedilol passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking Coreg. Use and dose must be determined by your doctor. Doses higher than 5 mg have not been studied in pediatric patients.



Important information

Get emergency medical help if you have any of these signs of an allergic reaction to carvedilol: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Staessen JA, Fagard R, Thijs L et al. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe Syst-Eur Trial Investigators. Lancet. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Dispense in tight container USP. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose. Take your next dose at the regular time. The dosage is based on your medical condition, response to treatment, age, and other you may be taking. Peterson ED, Gaziano JM, Greenland P. Recommendations for treating hypertension: what are the right goals and purposes? Talk to your pharmacist if you have questions about this information.



Consider reduced initial amlodipine dosage

Does amlodipine oral have side effects? AUC of approximately 40 to 60%. Chest pain resulting from exercise or physical exertion is usually reduced or prevented by amlodipine. This may tempt you to be too active. Make sure you discuss with your doctor a safe amount of exercise for your medical problem. American Heart Association Task Force on Practice Guidelines. Circulation. Mitka M. Groups spar over new hypertension guidelines. JAMA.



Dizziness; headache; persistent, dry cough

Take this medication on an empty or with a low- meal. not take within 1 hour before or 2 hours after a high-fat meal. Doing so may increase side effects. Do not skip doses or stop taking bisoprolol without first talking to your doctor. Stopping suddenly may make your condition worse or cause other serious heart problems. Allow the cuff to completely deflate. Dialysis: Artificial filtering of the blood to replace the lost function of damaged kidneys. There are no adequate and well-controlled studies in pregnant women. Kaplan NM. Choice of initial therapy for hypertension. JAMA. Nisoldipine is called a channel blocker. It works by relaxing vessels so can flow more easily. Taler SJ, Agarwal R, Bakris GL et al. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for management of blood pressure in CKD. Am J Kidney Dis. Some cholesterol medications can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. This drug has been used safely in patients with chronic obstructive pulmonary disease, well-compensated heart failure, peripheral vascular disease, diabetes mellitus, and with abnormal lipid profiles. So after I told him with no uncertain stance that the medicine was my problem, he then said to try something simple- lisinopril 20mg by itself! Use with caution. May make these conditions worse. Vincent J, Harris S, Foulds G et al. Amlodipine and grapefruit juice. Br J Clin Pharmacol. Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. MRHD on a body surface area basis, assuming a 50 kg woman.



Use of amlodipine

Izzo JL, Levy D, Black HR. Importance of systolic blood pressure in older Americans. Hypertension. Amlodipine passes into milk. It is unknown if olmesartan passes into milk. Consult your doctor before breast-feeding. In some patients, tenderness, swelling, or bleeding of the gums may appear soon after treatment with amlodipine is started. Brushing and flossing your teeth carefully and regularly and massaging your gums may help prevent this. See your dentist regularly to have your teeth cleaned. Check with your doctor or dentist if you have any questions about how to take care of your teeth and gums, or if you notice any tenderness, swelling, or bleeding of your gums. Antihypertensive effects of amlodipine persist for at least 24 hours after administration. Continued Do Allergy Shots Work for Everyone? Boehringer Ingelhein Pharmaceuticals, Inc. Twynsta telmisartan and amlodipine besylate tablets prescribing information. Ridgefield, CT; 2014 Dec. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use carvedilol only for the indication prescribed.



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Kaplan NM. Initial treatment of adult patients with essential hypertension. Part 2: alternating monotherapy is the preferred treatment. Pharmacotherapy. Julius S. Amlodipine in hypertension: an overview of the clinical dossier. J Cardiovasc Pharmacol. Bisoprolol is not approved for use by anyone younger than 18 years old. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Sandoz Pharmaceuticals Corp. DynaCirc isradipine capsules prescribing information. East Hanover, NJ; 1992 Jun. This drug is available at the lowest co-pay. It is not known whether bisoprolol is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. If you need to have any type of surgery, tell the surgeon ahead of time that you are using this medicine. This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.



What conditions does amlodipine treat

Lenfant C. The calcium channel blocker scare: lessons for the future. Circulation. You may open the Coreg CR capsule and sprinkle the medicine into a spoonful of pudding or applesauce to make swallowing easier. Swallow right away without chewing. Do not save the mixture for later use. Discard the empty capsule. Blocker Heart Attack Trial Research Group. A randomized trial of propranolol in patients with acute myocardial infarction: I. Mortality results. JAMA. Get emergency medical help if you have signs of an allergic reaction to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat. CYP3A4 inducers on amlodipine. Talk to your doctor or about lifestyle changes that might benefit you.



Amlodipine warnings

Store amlodipine at room temperature, between 59 and 86 degrees F 15 and 30 degrees C. Store away from heat, moisture, and light. Do not store in the bathroom. Keep amlodipine out of the reach of children and away from pets. Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators. Lancet. The following information addresses dosage of amlodipine in special populations. Dosages of drugs administered in fixed combination with amlodipine also may require adjustment in certain patient populations; the need for such dosage adjustments must be considered in the context of cautions, precautions, and contraindications specific to that population and drug. Get on the phone and go to the nearest emergency room if you have shortness of breath, a tight throat, or any other symptoms that worry you after getting your shot. Do I Have to Get a Shot? Drinking alcohol can further lower your blood pressure and may increase certain side effects of carvedilol. You should especially avoid drinking alcohol within 2 hours before or after taking extended-release carvedilol Coreg CR. Consider ACE inhibitor-induced cough in the differential diagnosis of cough. Don't breastfeed while you are taking LOTREL. Meditation usually involves slow, regular breathing and sitting quietly for at least 15 to 20 minutes. What is meditation used for? Sit up straight with your back against the chair, legs uncrossed. Store bisoprolol at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Glasser SP, Clark PI, Lipicky RJ et al. Exposing patients with chronic, stable, exertional angina to placebo periods in drug trials. JAMA. If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns. Older adults may be more sensitive to the side effects of this drug, including dizziness, increases in potassium level, and change in the amount of urine kidney problems. MRHD calculations assume a patient weight of 60 kg. An empty tablet shell may appear in your stool. Magnetic resonance imaging : A scanner uses radio waves in a magnetic field to make high-resolution images of the kidneys.



How should i take amlodipine

Although this medication is effective in preventing some people who already have severe may rarely develop worsening chest pain or a after starting this medication or increasing the dose. It is not known whether Zetia alone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Use effective birth control to prevent pregnancy while you are using ezetimibe with a statin medication. This medication comes in different sustained-action forms with different strengths. Check with your doctor or pharmacist that you are taking the correct dose and form. Do not take a different strength or form without checking with your doctor or pharmacist first. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Avoid eating foods that are high in fat or cholesterol. Zetia will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. You should not take ezetimibe with gemfibrozil. Low blood sugar hypoglycemia can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, confusion, irritability, dizziness, or feeling shaky. Always keep a source of sugar with you in case you have low blood sugar. Sugar sources include fruit juice, hard candy, crackers, raisins, and non-diet soda. Be sure your family and close friends know how to help you in an emergency. If you cannot locate a pulse, place the head of the stethoscope on a manual monitor or the arm cuff on a digital monitor in the same general area.



What is amlodipine

All medicines may cause side effects, but many people have no, or minor, side effects. Amlodipine is a calcium-channel blocking agent; a dihydropyridine derivative with an intrinsically long duration of action. Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems. Anon. Groups act to dispel concerns about calcium-channel blockers. Am J Health- Syst Pharm. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It may take up to 2 weeks before you get the full benefit of this product. Keep taking this product even if you feel well. Most people with not feel sick. Amlodipine reduces total peripheral resistance afterload and rate pressure product and thus myocardial oxygen demand at any given level of exercise in patients with exertional angina.



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Zetia may be taken at the same time with fenofibrate, or with a statin medication such as atorvastatin, lovastatin, simvastatin, pravastatin, or fluvastatin. Calcium-channel blockers are recommended as one of several preferred agents for the initial management of hypertension; other options include ACE inhibitors, angiotensin II receptor antagonists, and thiazide diuretics. 501 502 503 504 While there may be individual differences with respect to specific outcomes, these antihypertensive drug classes all produce comparable effects on overall mortality and cardiovascular, cerebrovascular, and renal outcomes. Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. AHA guidelines for the evaluation and management of chronic heart failure in the adult. J Am Coll Cardiol. Thadani U and the Amlodipine Study Group. Sorry, but maybe most others had doctors like mine that didn't give it a second thought that MAYBE. May increase dosage of the fixed combination after 2 weeks if additional BP control is needed up to maximum of amlodipine 10 mg, aliskiren 300 mg, and hydrochlorothiazide 25 mg once daily. When was amlodipine besylate Norvasc approved by the FDA? Joseffson M, Zackrisson AL, Ahlner J. Effect of grapefruit juice on the pharmacokineitcs of amlodipine. Eur J Clin Pharmacol. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. When used for initial therapy of hypertension in patients likely to require combination therapy with multiple antihypertensive agents, usual initial dosage is amlodipine 5 mg and telmisartan 40 mg once daily; initial dosage of amlodipine 5 mg and telmisartan 80 mg once daily may be used in patients requiring larger BP reductions. Check the label on the medicine for exact dosing instructions. Extrapyramidal syndrome may be associated with this drug. Report prolonged or to your doctor.



HDL in the blood

American Diabetes Association. Standards of medical care in diabetes--2014. Diabetes Care. You should not use Zetia if you have moderate to severe liver disease. You should not use ezetimibe with a "statin" cholesterol medicine if you have active liver disease, or if you are pregnant or breast-feeding a baby. So as I call it to the doctor, plan c is working! If it is within 12 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Tell your doctor about any other medicines or herbs and you take. Some interfere with the treatment or raise the risk of side effects. In patients who experience dose-limiting adverse effects of amlodipine, valsartan, or hydrochlorothiazide while receiving any dual combination of these drugs, may switch to the triple fixed-combination preparation containing a lower dose of that component. It is not known if this medication passes into milk. Consult your doctor before -feeding. Hg is 62, 80, or 85% with valsartan 320 mg daily alone, amlodipine 10 mg daily alone, or amlodipine combined with valsartan same dosages respectively. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Use: Management of hypertension, alone or with other antihypertensive agents What other drugs will affect bisoprolol? Using a needle inserted into the back, a small piece of kidney tissue is removed. Examining the kidney tissue under a microscope may help diagnose a kidney problem. The FDA approved amlodipine in July 1992. National Kidney Foundation Guideline. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. Check your regularly while taking this medication. Learn how to monitor your own pressure at home, and share the results with your doctor.



Do not share this medication with others

Available as amlodipine besylate; dosage expressed in terms of amlodipine. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Symptoms of severe hypoglycemia include extreme weakness, confusion, tremors, sweating, fast heart rate, trouble speaking, nausea, vomiting, rapid breathing, fainting, and seizure convulsions. What should I avoid while taking glyburide? Appropriate studies have not been performed on the relationship of age to the effects of amlodipine to treat high blood pressure in children younger than 6 years of age. Safety and efficacy have not been established. Your blood pressure will need to be checked often. Amlodipine should not be used for acute management of hypertensive crises. If you have severe hypoglycemia and cannot eat or drink, use a glucagon injection. Food does not affect bioavailability of amlodipine. Before taking amlodipine, tell your doctor if you have or liver disease. Safety and efficacy have not been established in patients younger than 6 years. Avoid drinking alcohol. It can increase some of the side effects of bisoprolol. SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension: final results of the Systolic Hypertension in the Elderly Program SHEP. JAMA. It is unknown if telmisartan passes into milk. Amlodipine passes into milk. Consult your doctor before breast-feeding. This drug may rarely cause muscle problems which can rarely lead to very serious conditions called and autoimmune myopathy.



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What other drugs will affect amlodipine


When Should I Call My Doctor?

This product may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist. Ameer B, Weintraub RA. Drug interactions with grapefruit juice. Clin Pharmacokinet. Lab tests, including blood pressure checks, may be performed while you use amlodipine. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. Anon. NHLBI panel stands by JNC V in response to Circulation CCB article; AIM report supports use of beta blockers for prevention of sudden cardiac death. F-D- C Rep.

Indications and usage of amlodipine

Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment. Avoid drinking alcohol within 2 hours before or after taking extended-release carvedilol Coreg CR. Also avoid taking medicines or other products that might contain alcohol. Alcohol may cause the carvedilol in Coreg CR to be released too quickly into the body. If you are taking amlodipine for angina, it will not relieve the pain of an acute attack if it is taken at the time of an acute attack. It prevents or reduces the number of angina attacks only if you take it on regular schedule. Take Coreg exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

General information about amlodipine

Get emergency medical help if you have any signs of an allergic reaction to glyburide: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Bailey DG, Arnold JMO, Spence JD. Grapefruit juice and drugs: how significant is the interaction? Alderman M, Madhavan S, Cohen H. Calcium antagonists and cardiovascular events in patients with hypertension and diabetes. Lancet. Minerals in urine form crystals stones which may grow large enough to block urine flow. It's considered one of the most painful conditions. Most kidney stones pass on their own but some are too large and need to be treated.

Reviews for amlodipine

LDL apheresis, dialysis liver disease, a certain structural heart problem aortic stenosis. How do I store LOTREL? High blood sugar from diabetes progressively damages the kidneys, eventually causing chronic kidney disease. Protein in the urine nephrotic syndrome may also result. National Heart, Lung, and Blood Institute. NHLBI panel reviews safety of calcium channel blockers. Rockville, MD; 1995 Aug 31. Press release. Angioedema associated with edema can be fatal.

Prisant LM, Carr AA, Nelson EB et al. Isradipine vs propranolol in hydrochlorothiazide-treated hypertensives: a multicenter evaluation. Arch Intern Med. This drug may make you dizzy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit beverages. Weber MA, Schiffrin EL, White WB et al. Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension. J Clin Hypertens Greenwich. ACE inhibitors, angiotensin II receptor antagonists. 69 70 95 108 109 500 501 504 However, diminished response to these other drug classes is largely eliminated when administered concomitantly with a calcium-channel blocker or thiazide diuretic.

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